Abstract: In the study of outgassing of materials, the Arrhenius formula is often used to calculate the acceleration factor of accelerated life experiments, using activation energy to characterize its relationship with temperature. However, the variation of the outgassing rate during the experiment is often neglected in current research, which results in deviations between theoretical models and actual results. Based on the Arrhenius formula, the relationship between it and the outgassing mechanism of metal material (304 stainless steel) and polymer material (polyimide) was investigated theoretically. Combining the activation energy and decay factor of outgassing, a unified mathematical model of acceleration factor is established and verified by two experimental methods (conduction method, boost method). The results showed that there were significant differences in the attenuation factors between polyimide and stainless steel due to the different outgassing mechanisms. The outgassing decay phenomenon of polyimide is evident, and it must be taken into account when calculating its acceleration factor. This study provides a theoretical basis for the accelerated life experiments of different materials and provides a basis for the subsequent calculation of the overall acceleration factor of multi material samples.