Abstract: vacuum critical to the safety of satellite high -power products and the life span of the track. After the satellite enters orbit, the temperature of the space environment changes dramatically and there is a significant error in deriving the vacuum degree inside the satellite using the isothermal release formula. Based on the characteristics of the material's adsorption with the characteristics of temperature changes, calculate the amount of gas released from satellite materials under variable temperature conditions, and proposes a satellite internal vacuum simulation calculation method. The simulation analysis of the interpretation of the internal materials of the temperature fluctuation environment has been performed, and the satellite communications cabin simulation results are changed over time under temperature mutation state. Compared with the actual measurement result, the simulation result error is less than 34%. This article provides theoretical basis for the estimation of satellites in the rail and ground vacuum experiment.